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DUPIXENT Dosing for Asthma

Not an Inhaler.
Not a Steroid.

DUPIXENT is something different: the only dual-targeting biologic treatment for moderate-to-severe asthma. It's taken by injection under the skin (subcutaneous injection). It is taken differently than oral steroids and inhalers.

WHAT YOU SHOULD KNOW

DUPIXENT can be given by your doctor in a clinic or doctor’s office, or self-administered at home.

If your healthcare provider decides that you or a caregiver can give DUPIXENT injections, you or your caregiver should
receive training on the right way to prepare and inject DUPIXENT.

In addition to the training from your doctor, explore the resources available in the Injection Support Center:

  • Supplemental injection video tutorials
  • Downloadable Instructions for Use
  • Testimonials from real patients
  • Mindful breathing exercises
GET SUPPLEMENTAL
INJECTION SUPPORT

RECOMMENDED DOSING FOR DUPIXENT

For adults with uncontrolled
moderate‑to‑severe eosinophilic or OCS dependent asthma

The recommended dose is specified in the appropriate tables below. Use DUPIXENT exactly as prescribed by your healthcare provider.

Talk to your doctor and download the detailed Instructions for Use for information on how to prepare and inject DUPIXENT and how to properly store and dispose of used DUPIXENT Pre-filled Syringes and Pre-filled Pens. Do not try to inject DUPIXENT until you have been shown the right way by your doctor.

 

The recommended dose of
DUPIXENT for patients 12+ years is:

Initial Dose

Subsequent
Doses

Adults, pediatric patients
(12+ years)

400 mg;
two 200‑mg
injections

Followed
by

200 mg
every
2 weeks

600 mg;
two 300‑mg
injections

Followed
by

300 mg
every
2 weeks

Patients with oral steroid dependent asthma or with moderate-to-severe eczema or adults with co-morbid chronic rhinosinusitis with nasal polyposis

600 mg;
two 300-mg
injections

Followed
by

300 mg
every
2 weeks

The recommended dose of
DUPIXENT for children 6-11 years is:

Initial and Subsequent Doses

Body weight 33 lb to under 66 lb

300 mg every 4 weeks

66 lb or more

200 mg every 2 weeks

For pediatric patients 6-11 years old with asthma and co-morbid moderate-to-severe eczema, follow the recommended dosage for pediatric patients 6-17 years with eczema.

WORRIED ABOUT MISSING A DOSE?

Follow these next steps if your
dosing schedule gets off track

If your dose schedule is every other week and you miss a dose of DUPIXENT: Give the DUPIXENT injection within 7 days from the missed dose, then continue with your original schedule. If the missed dose is not given within 7 days, wait until the next scheduled dose to give your DUPIXENT injection.

If your dose schedule is every 4 weeks and you miss a dose of DUPIXENT: Give the DUPIXENT injection within 7 days from the missed dose, then continue with your original schedule. If the missed dose is not given within 7 days, start a new every 4 week dose schedule from the time you remember to take your DUPIXENT injection.

Get tips to help avoid missing a dose
and stay on track with treatment
 

Transcript

RACHEL: I was a little surprised when I found out DUPIXENT would require an injection every two weeks. It was different than what I was used to. I was used to taking another pill or using another inhaler. I knew adding DUPIXENT was going to change my routine. It was going to be new, but over time I’ve gotten comfortable with it.

SHARRON: When I found out that DUPIXENT was an injectable, I was okay with it. If there was a chance that it could help get my severe asthma under control, then I was willing to do whatever I needed to do.

RACHEL: My doctor and nurses showed me how to properly self-inject. I am a registered nurse and I give injections at work, but I still needed to learn how to properly inject DUPIXENT myself.

SHARRON: Your doctor will walk you through the injection process. I also watched the video on DUPIXENT.com and followed the instructions.

RACHEL: DUPIXENT comes in a pre-filled syringe or pen and is a subcutaneous injection, which means it goes just underneath the skin.

SHARRON: I appreciate that there’s a pre-filled pen. I used a pre-filled syringe.

RACHEL: Before I started DUPIXENT, I told my doctor about all the medical conditions I had and medications I was taking.

SHARRON: My doctor and I talked about the potential benefits and risks of treatment, including the most common side effects such as injection site reactions...

...and some serious side effects including allergic reactions that can sometimes be severe, inflammation of your blood vessels, and joint aches and pain.

SHARRON: Well early on, my doctor steered me to the patient support program, DUPIXENT MyWay, and I’m so glad that he did. They’ve been a great resource and even offered to send a nurse to my home to help with further instruction.

RACHEL: I was really blown away by how much support the DUPIXENT MyWay team provides. You feel that they are in this with you and they’re there to help!

SHARRON: I like to do my self-injection in the evening in a quiet part of the house where I can focus. My routine is to do the selfinjection after I’ve gotten out of the shower.

RACHEL: I write DUPIXENT on my calendar at home and in my pocket calendar to help me remember when to take it. I’ve got my self-injection routine down. I’m comfortable with it.

VO:

TWO WAYS TO TAKE DUPIXENT

Dupixent® (dupilumab) Pre-filled Pen (200 mg or 300 mg) for ages 6+ years

Pre-filled Pen

  • Hear and see when your dose is being delivered
  • Hidden needle
  • Available in 200 mg and 300 mg dose for patients
    aged 6+ years
Dupixent® (dupilumab) Pre-filled Syringe (200 mg, or 300 mg) with needle shield for ages 12+ years

Pre-filled Syringe

  • Needle shield for safety
  • Full-dose delivery when plunger is completely depressed
  • Available in 200 mg and 300 mg dose

NURSE EDUCATORS ARE HERE TO HELP

Get live assistance online,
over the phone, or in person

In addition to the training from your doctor, DUPIXENT MyWay® Nurse Educators can provide supplemental injection training with a training kit and syringe for practice in a variety of ways.

Dupixent Myway® Logo

For more information, dial
1-844-DUPIXENT (1‑844‑387‑4936),
option 1

Monday-Friday, 8 am-9 pm ET

frequently asked questions

If your dose schedule is every 4 weeks and you miss a dose of DUPIXENT: Give the DUPIXENT injection within 7 days from the missed dose, then continue with your original schedule. If the missed dose is not given within 7 days, start a new every 4 week dose schedule from the time you remember to take your DUPIXENT injection.

If your dose schedule is every other week and you miss a dose of DUPIXENT: Give the DUPIXENT injection within 7 days from the missed dose, then continue with your original schedule. If the missed dose is not given within 7 days, wait until the next scheduled dose to give your DUPIXENT injection.

SET UP INJECTION REMINDERS

No, you should always follow your healthcare provider’s instructions for dosing and how to give injections.

The recommended dose of
DUPIXENT for patients 12+ years is:

The recommended dose of
DUPIXENT for children 6-11 years is:

For pediatric patients 6-11 years old with asthma and co‑morbid moderate-to-severe eczema, follow the recommended dosage for pediatric patients 6-17 years with eczema.

Talk to your healthcare provider and see the detailed Instructions for Use that come with DUPIXENT for information on how to prepare and inject DUPIXENT and how to properly store and throw away (dispose of) used DUPIXENT Pre-filled Syringes or DUPIXENT Pre-filled Pens prior to taking the drug. The DUPIXENT Pre-filled Pen is only in use for adults and children 6 years of age and older.

DUPIXENT is a biologic—an injectable type of medication that is processed in the body differently than oral medications (pills) or steroids. Today, different biologics are used to treat many conditions you may be familiar with.