WHY LET ASTHMA
HOLD
YOU BACK?

DUPIXENT was studied in 3 clinical trials with more than 2,800 people 12 years of age and older with moderate-to-severe asthma.

BENEFITS WITH EVERY BREATH

Read more about the clinical studies for DUPIXENT in asthma patients.

Improved lung
function
in as little as

UP TO 81%
FEWER ASTHMA ATTACKS*†

86% OF PEOPLE
REDUCED OR ELIMINATEd THEIR
ORAL STEROID DOSE‡

In a study of people dependent
on oral corticosteroids.

*In those with high eosinophil counts (a type of white blood cell).

†The annual rate of severe asthma attacks was 0.20 with DUPIXENT 300 mg vs 1.04 with placebo.

‡In a clinical study with DUPIXENT 300 mg + Standard of Care vs 68% with placebo + Standard of Care.

Do not stop taking your corticosteroid medicines unless instructed by your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine to come back.

What You Should Know About the Patients in These Studies:

≈49

Average age

2

Average number of
asthma attacks in previous year

≈64%

On high-dose
inhaled
corticosteroids

Dupixent had a

demonstrated safety
profile in clinical trials

The most common side effects include:

  • Injection site reactions
  • High count of a certain white
    blood cell (eosinophilia)
  • Pain in the throat
    (oropharyngeal pain)

View the possible side effects of DUPIXENT in patients with moderate-to-severe eosinophilic or oral corticosteroid dependent asthma.

RESULTS IN CHILDREN

DUPIXENT was also proven to improve lung function, prevent asthma attacks and reduce steroid
bursts in children 6-11 years.

EXPLORE THE RESULTS

HAVE A PRODUCTIVE CONVERSATION WITH YOUR DOCTOR

Personalize your doctor discussion guide

Our goal is for you or your loved one to get the most out of your visit to the doctor. Fill out our personalized discussion guide to help you have a productive conversation during your next visit.

PERSONALIZE YOUR GUIDE

Video Resources To Get
You Started

Learn what happens once you’ve been prescribed treatment, the importance of staying on track with your DUPIXENT treatment and the role you and your doctor can play.

CONSIDERING DUPIXENT

SHARRON: I have lived with severe asthma most of my life. It developed early on when I was in middle school, and then as an adult, I had to use my rescue inhaler very frequently and the nebulizer as well.

RACHEL: I was diagnosed with severe asthma at the age of ten.

I had a lot of coughing, wheezing, feeling short of breath. My chest would get tight. We tried a lot of different asthma medications, but I would still end up in the hospital a couple of times a year. It had a really big impact on my life.

SHARRON: So, I love to sing, and singing was challenging to carry a note all the way through. I just couldn’t breathe. It was just hard to breathe.

RACHEL: The hardest thing to deal with was my wheezing. It was all the time. If we were sitting in a quiet classroom, the people next to me could hear me wheezing.

SHARRON: My asthma was not under control. Every day I woke up knowing that there’s a chance that I could have a severe asthma attack and go to the ER. It was definitely a weight on my mind with living like that, and I felt hopeless.

RACHEL: I had a really bad asthma attack when I was twenty-five years old that resulted in me being in the hospital for a week and after that, I was like, “Enough is enough!” I have to do something more to control my asthma.

SHARRON: So, my doctor treated my asthma with rescue inhalers, anti-inflammatories, oral steroids and long-acting inhalers. They weren’t managing the asthma well; it was not controlled.

One day on a follow-up appointment, my doctor brought up DUPIXENT as an addon therapy. He talked about it being a biologic, what that was, and I was ready for it.

If there was a chance that it could help control my asthma, then I was ready for it and willing to do whatever I needed to do.

RACHEL: When my doctor suggested DUPIXENT, I was open to it. We had a candid conversation. I asked a lot of questions. She explained to me what was going on in my body and that DUPIXENT could work for patients like me, so I wanted to try it.

RACHEL: Before I started DUPIXENT, I told my doctor about all the medical conditions I had and medications I was taking.

SHARRON: My doctor and I talked about the potential benefits and risks of treatment, including the most common side effects such as injection site reactions, and some serious side effects including allergic reactions that can sometimes be severe, inflammation of your blood vessels, and joint aches and pain.

RACHEL: After starting DUPIXENT, I was able to do some of my simple, everyday activities without my asthma getting in the way as often, like running around the yard with my dogs, helping with the outdoor chores.

SHARRON: Over time I noticed that the wheezing decreased. I didn’t have to use my rescue inhaler as often, and I think the best of all was that I was able to sing and hold the note.

RACHEL: I never thought that I would be where I am in my asthma journey. It’s a very good feeling. I feel a lot of relief knowing that my asthma is better controlled.

SHARRON: It feels great to be able to manage my asthma better.

RACHEL: I’ve learned to be a good advocate for myself and that I do not have to accept uncontrolled asthma.

VO:

Important Safety
Information and Indication

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have a parasitic (helminth) infection
  • are scheduled to receive any vaccinations. You should not receive a "live vaccine" right before and during treatment with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines or use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms: breathing problems or wheezing, swelling of the face, lips, mouth, tongue, or throat, fainting, dizziness, feeling lightheaded, fast pulse, fever, hives, joint pain, general ill feeling, itching, skin rash, swollen lymph nodes, nausea or vomiting, or cramps in your stomach-area.
  • Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your healthcare provider right away if you have: rash, chest pain, worsening shortness of breath, a feeling of pins and needles or numbness of your arms or legs, or persistent fever.
  • Joint aches and pain. Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.

The most common side effects in patients with asthma include injection site reactions, high count of a certain white blood cell (eosinophilia), pain in the throat (oropharyngeal pain), and parasitic (helminth) infections.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed by your healthcare provider. It’s an injection given under the skin (subcutaneous injection). Your healthcare provider will decide if you or your caregiver can inject DUPIXENT. Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider. In children 12 years of age and older, it’s recommended DUPIXENT be administered by or under supervision of an adult. In children 6 to less than 12 years of age, DUPIXENT should be given by a caregiver.

Please see accompanying full Prescribing Information including Patient Information.

Indication

DUPIXENT is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe eosinophilic or oral steroid dependent asthma in adults and children 6 years of age and older whose asthma is not controlled with their current asthma medicines. DUPIXENT helps prevent severe asthma attacks (exacerbations) and can improve your breathing. DUPIXENT may also help reduce the amount of oral corticosteroids you need while preventing severe asthma attacks and improving your breathing. DUPIXENT is not used to treat sudden breathing problems. It is not known if DUPIXENT is safe and effective in children with asthma under 6 years of age.

Starting DUPIXENT

Did you know that each time your DUPIXENT® (dupilumab) is shipped to you, you’re getting more than just your medicine in that delivery box?

It’s true!

DUPIXENT is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe eosinophilic or oral steroid dependent asthma in adults and children 6 years of age and older whose asthma is not controlled with their current asthma medicines. DUPIXENT is not used to treat sudden breathing problems.

With each delivery of DUPIXENT, you’re also getting an opportunity for better control of your asthma.

Just imagine what that improvement could mean for you.

Each time you open that box, think about how DUPIXENT may help you do more of what you want in life.

What could you do with more freedom from asthma?

What could you spend more of your time doing?

And remember, if you take your DUPIXENT every other week as prescribed, you’re not only working to help prevent attacks, you’re also giving yourself the opportunity to do more with less asthma.

And don’t forget, DUPIXENT MyWay® Nurse Educators are just a phone call away.

Important Safety
Information and Indication

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have a parasitic (helminth) infection
  • are scheduled to receive any vaccinations. You should not receive a "live vaccine" right before and during treatment with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines or use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms: breathing problems or wheezing, swelling of the face, lips, mouth, tongue, or throat, fainting, dizziness, feeling lightheaded, fast pulse, fever, hives, joint pain, general ill feeling, itching, skin rash, swollen lymph nodes, nausea or vomiting, or cramps in your stomach-area.
  • Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your healthcare provider right away if you have: rash, chest pain, worsening shortness of breath, a feeling of pins and needles or numbness of your arms or legs, or persistent fever.
  • Joint aches and pain. Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.

The most common side effects in patients with asthma include injection site reactions, high count of a certain white blood cell (eosinophilia), pain in the throat (oropharyngeal pain), and parasitic (helminth) infections.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed by your healthcare provider. It’s an injection given under the skin (subcutaneous injection). Your healthcare provider will decide if you or your caregiver can inject DUPIXENT. Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider. In children 12 years of age and older, it’s recommended DUPIXENT be administered by or under supervision of an adult. In children 6 to less than 12 years of age, DUPIXENT should be given by a caregiver.

Please see accompanying full Prescribing Information including Patient Information.

Indication

DUPIXENT is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe eosinophilic or oral steroid dependent asthma in adults and children 6 years of age and older whose asthma is not controlled with their current asthma medicines. DUPIXENT helps prevent severe asthma attacks (exacerbations) and can improve your breathing. DUPIXENT may also help reduce the amount of oral corticosteroids you need while preventing severe asthma attacks and improving your breathing. DUPIXENT is not used to treat sudden breathing problems. It is not known if DUPIXENT is safe and effective in children with asthma under 6 years of age.

TAKING DUPIXENT

Transcript

RACHEL: It's really important to me to take DUPIXENT as directed by my doctor. I make it a priority. My severe asthma is something I need to keep controlled. It's not going away. It's something I live with, and I need to manage it.

SHARRON: I understand that my severe asthma is a chronic condition, there will always be underlying inflammation, and that my severe asthma will never quit and neither can I.

RACHEL: I feel motivated to stay on my treatment schedule, because I know what it feels like not to be able to breathe well, and I want to do everything I can to help avoid being in that situation.

SHARRON: What motivates me to stay on treatment is knowing that my current treatment plan is working. With DUPIXENT I’m able to do more of what I want to do and with less asthma.

RACHEL: Having a routine has definitely helped me stay on track. I take my DUPIXENT every two weeks. It’s a system I’m comfortable with.

SHARRON: So, I have a DUPIXENT reminder on my calendar and an alarm set on my phone. It’s scheduled for every two weeks, and it’s like a ritual for me. It is how I take care of myself.

RACHEL: When I first started out on DUPIXENT, the DUPIXENT MyWay® patient support program was really helpful. They are there to help you answer questions about DUPIXENT. They can help you set up reminders to start and maintain a routine. But remember, your doctor is always the best source of information.

SHARRON: My doctor recommended that I reach out to DUPIXENT MyWay after he wrote the prescription. I’m so glad he did! They’ve been a tremendous resource for me, and it’s good to know that I can reach out to them.

SHARRON: Before I started DUPIXENT, I told my doctor about all the medical conditions I had and medications I was taking.

RACHEL: My doctor and I talked about the potential benefits and risks of treatment, including the most common side effects such as injection site reactions, and some serious side effects including allergic reactions that can sometimes be severe, inflammation of your blood vessels, and joint aches and pain.

SHARRON: Over time, I’ve definitely gotten more used to taking DUPIXENT. It’s a part of my life, just like going to the doctor.

RACHEL: I am comfortable taking DUPIXENT every two weeks. I know that it helps control my asthma, and I feel that it's helping prevent me from another asthma attack. It’s what my doctor and I decided I need to do.

VO:

Important Safety
Information and Indication

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have a parasitic (helminth) infection
  • are scheduled to receive any vaccinations. You should not receive a "live vaccine" right before and during treatment with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines or use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms: breathing problems or wheezing, swelling of the face, lips, mouth, tongue, or throat, fainting, dizziness, feeling lightheaded, fast pulse, fever, hives, joint pain, general ill feeling, itching, skin rash, swollen lymph nodes, nausea or vomiting, or cramps in your stomach-area.
  • Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your healthcare provider right away if you have: rash, chest pain, worsening shortness of breath, a feeling of pins and needles or numbness of your arms or legs, or persistent fever.
  • Joint aches and pain. Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.

The most common side effects in patients with asthma include injection site reactions, high count of a certain white blood cell (eosinophilia), pain in the throat (oropharyngeal pain), and parasitic (helminth) infections.

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed by your healthcare provider. It’s an injection given under the skin (subcutaneous injection). Your healthcare provider will decide if you or your caregiver can inject DUPIXENT. Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider. In children 12 years of age and older, it’s recommended DUPIXENT be administered by or under supervision of an adult. In children 6 to less than 12 years of age, DUPIXENT should be given by a caregiver.

Please see accompanying full Prescribing Information including Patient Information.

Indication

DUPIXENT is a prescription medicine used with other asthma medicines for the maintenance treatment of moderate-to-severe eosinophilic or oral steroid dependent asthma in adults and children 6 years of age and older whose asthma is not controlled with their current asthma medicines. DUPIXENT helps prevent severe asthma attacks (exacerbations) and can improve your breathing. DUPIXENT may also help reduce the amount of oral corticosteroids you need while preventing severe asthma attacks and improving your breathing. DUPIXENT is not used to treat sudden breathing problems. It is not known if DUPIXENT is safe and effective in children with asthma under 6 years of age.

Go to the DUPIXENT Dosing for Asthma page to learn more about dosing and administration options.

EXPLORE DUPIXENT DOSING

frequently asked questions

In clinical trials, the impact of DUPIXENT on lung function was studied in patients 6 to 11 years of age and patients 12 years of age and older. Patients in each age group saw improved lung function in as little as 2 weeks.

Learn how DUPIXENT helped treat children 6 to 11 years old with their moderate-to-severe asthma.

RESULTS IN CHILDREN
AGES 6-11 YEARS

DUPIXENT can cause serious side effects, including:

  • Allergic reactions. DUPIXENT can cause reactions that can sometimes be severe. Stop using DUPIXENT and go to the nearest hospital emergency room if you get any of the following symptoms:
  • breathing problems or wheezing
  • fast pulse
  • fever
  • general ill feeling
  • swollen lymph nodes
  • swelling of the face, lips, mouth,
    tongue, or throat
  • hives
  • itching
  • nausea or vomiting
  • fainting, dizziness, feeling
    lightheaded
  • joint pain
  • skin rash
  • cramps in your stomach-area
  • Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive DUPIXENT. This may happen in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by DUPIXENT. Tell your healthcare provider right away if you have:
  • rash
  • worsening shortness of breath
  • persistent fever
  • chest pain
  • a feeling of pins and needles or
    numbness of your arms or legs
  • Joint aches and pain. Joint aches and pain can happen in people who use DUPIXENT. Some people have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.

The most common side effects of DUPIXENT include:

  • injection site reactions
  • pain in the throat (oropharyngeal pain)
  • high count of a certain white blood cell (eosinophilia)
  • parasitic (helminth) infections

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all of the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Do not stop taking your corticosteroid medicines unless instructed by your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine to come back.