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HOW DUPIXENT WORKS

DUPIXENT is a Unique Treatment Approach

DUPIXENT targets an underlying source of inflammation that contributes to EoE, reducing EoE symptoms.

Until DUPIXENT, treatment options were limited in what they could achieve for people with EoE. Common treatment approaches include proton
pump inhibitors (PPIs), swallowed topical corticosteroids, and food elimination diets.

These treatment methods are prescribed and may provide temporary symptom relief from EoE. DUPIXENT is the first FDA-approved treatment for this
chronic condition.

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(ages 12+ years) 

WHAT IS A BIOLOGIC?

DUPIXENT is a biologic that blocks 2 of the key sources of Type 2 inflammation in the esophagus.

  • DUPIXENT is a form of medicine called a biologic. It is not an immunosuppressant or a steroid.
  • Biologics are processed in the body differently than oral or topical medications. Most biologic medications come as liquids and should be administered by injection. Today, different biologics are used to treat many conditions you may be familiar with.

 

DUPIXENT Dosing for EoE

Learn about the methods of administration for DUPIXENT,
recommended dosing, and much more.

EXPLORE DUPIXENT
DOSING

Download the Patient Brochure

Looking for DUPIXENT information you can download or print out? Download the patient brochure to have on hand.

Get the DUPIXENT Patient Brochure

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FIND A SPECIALIST WHO CAN TREAT EoE

EoE can be a complicated condition to manage. Discover the benefits of partnering with a specialist who can help create a customized treatment plan for you or your loved one.

Use this Healthgrades™ tool to easily find a nearby specialist with experience in treating patients suffering from eosinophilic esophagitis (EoE).

Sanofi US and Regeneron do not endorse or recommend any particular physician, and search results do not include a comprehensive list of doctors in your area.

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FREQUENTLY ASKED QUESTIONS

DUPIXENT is indicated for the treatment of adult and pediatric patients aged 1 year and older who weigh at least 33 lb (15 kg) with eosinophilic esophagitis (EoE).

Fill out our personalized doctor discussion guide to help guide your conversation with your doctor and discover whether DUPIXENT may be right for you.

DUPIXENT targets an underlying source of inflammation, which contributes to EoE.

Before using DUPIXENT, tell your doctor about all your medical conditions, including if you:

  • have a parasitic (helminth) infection.
  • are scheduled to receive any vaccinations. You should not receive a "live vaccine" right before and during treatment with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical, or inhaled corticosteroid medicines or if you have EoE and asthma and use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

In May 2022, the U.S. Food and Drug Administration (FDA) approved DUPIXENT® to treat patients with EoE aged 12 years and older, weighing at least 40 kg. In January 2024, the FDA expanded DUPIXENT’s approval to treat patients with EoE aged 1 year and older, weighing at least 15 kg.