Results for
COPD Patients

DUPIXENT is a biologic that blocks two of the key sources of Type 2 inflammation, a known cause of COPD flare-ups.

WHEN USED WITH COPD
INHALERS,* DUPIXENT CAN:

Reduce the number of
flare-ups
Help you breathe better
with long-lasting lung
function improvement
Lead to improvement
in patients’ day-to-day
lives

View the possible side effects of DUPIXENT in patients with inadequately controlled chronic obstructive
pulmonary disease. The most common side effects associated with DUPIXENT were injection site reactions,
common cold symptoms (nasopharyngitis), high count of a certain white blood cell (eosinophilia), viral
infection, back pain, inflammation inside the nose (rhinitis), diarrhea, gastritis, joint pain (arthralgia),
toothache, headache, and urinary tract infection.

*COPD inhalers are considered standard of care (SOC), which refers to a typical treatment approach
prescribed by a healthcare professional for COPD.

Assessed by SGRQ, a quality of life tool which measures COPD symptoms, physical activity, emotional well-
being, and social functioning. In two trials, 51% of patients who received DUPIXENT + SOC experienced a
quality of life improvement vs 43% and 47% with placebo + SOC. In one trial, results are descriptive, no
definitive conclusions can be made.

DUPIXENT HAD A DEMONSTRATED SAFETY PROFILE IN CLINICAL TRIALS

The most common side effects in COPD include:

injection site reactions, common cold symptoms (nasopharyngitis), high count of a certain white blood cell (eosinophilia), viral
infection, back pain, inflammation inside the nose (rhinitis), diarrhea, gastritis, joint pain (arthralgia), toothache, headache,
and urinary tract infection

HAVE A PRODUCTIVE CONVERSATION WITH YOUR PULMONOLOGIST

Conversations with your pulmonologist can be tough, but explaining how COPD truly affects your life is a key part of your treatment journey.

Ready to start the dialogue? Download, print, and complete our doctor discussion guide, which is loaded with crucial questions and topics to discuss. Take it with you to your next appointment to make the visit count.

Not an actual patient

FIND A NEARBY PULMONOLOGIST WHO TREATS COPD

By partnering with a pulmonologist, together
you can create a personalized treatment
plan that may help you or your loved one
better manage COPD symptoms.

FREQUENTLY ASKED QUESTIONS

The effect of DUPIXENT on oral steroid use in COPD was not studied. Do not stop taking your corticosteroid medicines unless instructed by your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine to come back.

The average age of patients in these studies was 65. Patients had an average of 2.2 moderate-to-severe flare-ups in the past year, and an average time of 9 years since their initial COPD diagnosis.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions. DUPIXENT can cause reactions that can sometimes be severe. Stop using DUPIXENT and go to the nearest hospital emergency room if you get any of the following symptoms:
  • breathing problems or wheezing
  • fast pulse
  • fever
  • general ill feeling
  • swollen lymph nodes
  • swelling of the face, lips, mouth, tongue, or throat
  • hives
  • itching
  • nausea or vomiting
  • fainting, dizziness, feeling lightheaded
  • joint pain
  • skin rash
  • cramps in your stomach-area
  • Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vison, such as blurred vision. Your healthcare provider may send you to an ophthalmologist for an exam if needed.
  • Joint aches and pain. Joint aches and pain can happen in people who use DUPIXENT. Some people have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.

The most common side effects of DUPIXENT include:

  • injection site reactions
  • common cold symptoms (nasopharyngitis)
  • high count of a certain white blood cell (eosinophilia)
  • viral infection
  • back pain
  • Inflammation inside the nose (rhinitis)
  • diarrhea
  • gastritis
  • joint pain (arthralgia)
  • toothache
  • headache
  • urinary tract infection

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all of the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.