ATOPIC DERMATITIS IS THE MOST COMMON FORM OF ECZEMA

You or your loved one’s eczema could be atopic dermatitis and might be uncontrolled
despite treatment with topical prescription treatments.
 

WHAT CAUSES ECZEMA?

Eczema is caused in part by an overactive immune system, which causes more inflammation than
normal inside the body. This inflammation can lead to itching and rashes on the skin’s surface.

THE ITCH-SCRATCH CYCLE

Itching
Immune cells in the skin send
inflammatory signals to the surface.
This is what makes you think, "I really
need to scratch my skin."

Scratching
When you start scratching, you can further
break down the outer layer of skin cells and
allow germs, irritants, and allergens to
penetrate your body.

Inflammatory Signals
In response to germs, irritants, and allergens, your immune cells continue to send inflammatory signals to the surface, causing even more redness and itching. The cycle continues.

If your current topical prescription medication is not enough to control your moderate-to-severe eczema, you may want to explore another option.

LEARN HOW DUPIXENT WORKS

Talk to an eczema specialist if you or your loved one (ages 6+ months):

Hide skin from others

Have eczema that keeps
coming back and is
uncontrolled by topicals

Take oral steroids or
immunosuppressants
more
than once a year.

FACTS ABOUT ECZEMA (ATOPIC DERMATITIS)

  • You or your loved one’s eczema could be more than a skin condition. It could be atopic dermatitis, the most common form of eczema, and might be uncontrolled despite the use of topical prescription treatments.
  • Eczema (atopic dermatitis) is an immunological disease where the immune system causes more inflammation than normal.
  • An overactive immune system under the surface may lead to increased inflammation on the surface and is a contributing factor to the itchy patches on the skin.
  • Eczema (atopic dermatitis) commonly appears on the face, hands, knees, neck, elbows, and ankles.
  • Experiencing frequent flare-ups while using topical prescription therapies may mean that moderate-to-severe eczema (atopic dermatitis) is not well controlled.

WHAT DOES ECZEMA LOOK LIKE?

Learn how eczema signs and symptoms may present themselves based on your skin tone, and hear from a patient who wondered if her eczema was severe enough for DUPIXENT.

ECZEMA ACROSS SKIN TONES

Transcript

VO:
DUPIXENT is a prescription medicine used to treat adults and children 6 months of age and older with moderate-to-severe eczema (atopic dermatitis or AD) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 months of age.

Important Safety Information

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Please see additional Important Safety Information throughout this video and adjacent links for full Prescribing Information.

Individual results with DUPIXENT may vary.

Sponsored by Regeneron and Sanofi.

SANDRI JOHNSON: Hi. I’m Sandri Johnson. I’m a dermatology nurse practitioner. In my practice, I regularly see patients of varying ethnicities and so many different skin types. And when it comes to uncontrolled moderate-to-severe atopic dermatitis (or eczema), my patients all have different experiences.

Generally, if a patient has lighter skin, eczema causes inflamed pink or even deep red lesions.

On darker skin, the lesions usually appear as dark brown or purple or even ashy patches. Darker skin can get thick in areas that the patient scratches a lot.

People with different skin tones tend to see eczema show up on different parts of their bodies.

In lighter skin tones, we tend to see it in the folds of the skin, like the bends of the elbows or the knees.

Whereas in darker skin, we often see thick dry patches in the lower extremities.

Of course, how and where it presents can change over time in any skin type.

Also, the impact of eczema on the skin can vary especially when it comes to itching and scratching.

Scratching can lead to scarring and discoloration, which can be more noticeable in darker skin.

The discoloration in lighter skin might not be as noticeable.

So, eczema can be different for everyone. If yours doesn’t look quite like someone else’s, it’s okay.

The important thing is that you understand your eczema and advocate for yourself.

Ask questions and find a provider who can work with you to find an appropriate treatment option that will fit your individual needs.

Thanks for watching!

Important Safety Information and Indication

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have eye problems.
  • have a parasitic (helminth) infection.
  • are scheduled to receive any vaccinations. You should not receive a “live vaccine” right before and during treatment with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical or inhaled corticosteroid medicines or if you have atopic dermatitis and asthma and use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms: breathing problems or wheezing, swelling of the face, lips, mouth, tongue, or throat, fainting, dizziness, feeling lightheaded, fast pulse, fever, hives, joint pain, general ill feeling, itching, skin rash, swollen lymph nodes, nausea or vomiting, or cramps in your stomach-area.
  • Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision, such as blurred vision. Your healthcare provider may send you to an ophthalmologist for an eye exam if needed.
  • Joint aches and pain. Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.

The most common side effects in patients with eczema include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, dry eye, cold sores in your mouth or on your lips, and high count of a certain white blood cell (eosinophilia).

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed by your healthcare provider. It’s an injection given under the skin (subcutaneous injection). Your healthcare provider will decide if you or your caregiver can inject DUPIXENT. Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider. In children 12 years of age and older, it’s recommended DUPIXENT be administered by or under supervision of an adult. In children 6 months to less than 12 years of age, DUPIXENT should be given by a caregiver.

Please see accompanying full Prescribing Information including Patient Information.

Indication

DUPIXENT is a prescription medicine used to treat adults and children 6 months of age and older with moderate-to-severe eczema (atopic dermatitis or AD) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 months of age.

WHEN IS ECZEMA UNCONTROLLED?

Transcript

VO:

DUPIXENT is a prescription medicine used to treat adults and children 6 months of age and older with moderate-to-severe eczema (atopic dermatitis or AD) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 months of age.

Important Safety Information

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Please see additional Important Safety Information throughout this video and adjacent links for full Prescribing Information.

Individual results with DUPIXENT may vary.

Sponsored by Regeneron and Sanofi.

Rachel:

Hi, I’m Rachel, and I want to share with you one big misconception I had about my severe atopic dermatitis. And that is… I never really thought about how serious it could be. In my mind, it was just this annoying condition I had to deal with and could get by with some prescription creams and ointments.

So, when my doctor recommended DUPIXENT, I was a little surprised. The idea of injecting myself was new to me. I mean, I’d heard of self-injections for other diseases like diabetes, but not for eczema. And, to me, having an injection for something happening on my skin was more than I expected.

I remember thinking, “Is this really the point I’ve reached in treating my eczema?”

But then again, I tried different prescription creams and ointments. I even made dietary changes like cutting out dairy and meat. I wasn’t getting the results I was looking for. And hoping that it would just go away was wishful thinking. I realized my eczema was serious, and I needed to make a change.

That’s when my doctor and I took the next step and moved forward with DUPIXENT. And now, I see my self-injection with DUPIXENT every two weeks as a part of my life.

So, that’s a little bit of My DUPIXENT Journey. Thanks for watching!

Important Safety Information and Indication

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have eye problems.
  • have a parasitic (helminth) infection.
  • are scheduled to receive any vaccinations. You should not receive a “live vaccine” right before and during treatment with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical or inhaled corticosteroid medicines or if you have atopic dermatitis and asthma and use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms: breathing problems or wheezing, swelling of the face, lips, mouth, tongue, or throat, fainting, dizziness, feeling lightheaded, fast pulse, fever, hives, joint pain, general ill feeling, itching, skin rash, swollen lymph nodes, nausea or vomiting, or cramps in your stomach-area.
  • Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision, such as blurred vision. Your healthcare provider may send you to an ophthalmologist for an eye exam if needed.
  • Joint aches and pain. Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.

The most common side effects in patients with eczema include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, dry eye, cold sores in your mouth or on your lips, and high count of a certain white blood cell (eosinophilia).

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed by your healthcare provider. It’s an injection given under the skin (subcutaneous injection). Your healthcare provider will decide if you or your caregiver can inject DUPIXENT. Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider. In children 12 years of age and older, it’s recommended DUPIXENT be administered by or under supervision of an adult. In children 6 months to less than 12 years of age, DUPIXENT should be given by a caregiver.

Please see accompanying full Prescribing Information including Patient Information.

Indication

DUPIXENT is a prescription medicine used to treat adults and children 6 months of age and older with moderate-to-severe eczema (atopic dermatitis or AD) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 months of age.

UNDERSTAND YOUR SYMPTOMS

Transcript

VO:

DUPIXENT is a prescription medicine used to treat adults and children 6 months of age and older with moderate-to-severe eczema (atopic dermatitis or AD) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 months of age.

Do not use if are allergic to dupilumab or to any of the ingredients in DUPIXENT.

Please stay tuned until the end of the video for full Indication and Important Safety Information.

Wondering if DUPIXENT® (dupilumab) may be right for you? Think about how uncontrolled moderate-to-severe eczema (atopic dermatitis) impacts your skin.

Could flare-ups cause unbearable itch and skin lesions?

Are you covering up your skin?

Have you experienced uncontrolled symptoms, such as red, grey, brown, or purple dry patches (depending on your skin color) with a rash that may bleed or ooze when scratched, or thickening and hardening of the skin, even with the use of prescription therapies used on the skin (topicals)?

Eczema symptoms can vary, but regardless of how moderate-to-severe eczema affects your skin, treating what you see on the surface with topicals may not be enough.

If your symptoms keep coming back even with topical prescription steroids and creams, maybe it’s time to also consider a treatment that targets a source of inflammation beneath the skin to help manage your itch and lesions.

What if you could get one step ahead of your eczema?

What if some relief is possible?

Clearer skin? Less itch? Imagine the possibilities with DUPIXENT. Adults in clinical trials saw clear or almost clear skin at 16 weeks and some saw improvement in itch at 2 weeks.

That’s a difference you can see and feel. You should not use DUPIXENT if you are allergic to dupilumab or to any of the ingredients in DUPIXENT.

The most common side effects in patients with atopic dermatitis include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, dry eye, cold sores in your mouth or on your lips, and high count of a certain white blood cell (eosinophilia).

So, talk to your healthcare provider about how DUPIXENT may help heal your skin from within.

INDICATION

DUPIXENT is a prescription medicine used to treat adults and children 6 months of age and older with moderate-to-severe eczema (atopic dermatitis or AD) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 months of age.

Important Safety Information and Indication

Do not use if you are allergic to dupilumab or to any of the ingredients in DUPIXENT®.

Before using DUPIXENT, tell your healthcare provider about all your medical conditions, including if you:

  • have eye problems.
  • have a parasitic (helminth) infection.
  • are scheduled to receive any vaccinations. You should not receive a “live vaccine” right before and during treatment with DUPIXENT.
  • are pregnant or plan to become pregnant. It is not known whether DUPIXENT will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known whether DUPIXENT passes into your breast milk.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Especially tell your healthcare provider if you are taking oral, topical or inhaled corticosteroid medicines or if you have atopic dermatitis and asthma and use an asthma medicine. Do not change or stop your corticosteroid medicine or other asthma medicine without talking to your healthcare provider. This may cause other symptoms that were controlled by the corticosteroid medicine or other asthma medicine to come back.

DUPIXENT can cause serious side effects, including:

  • Allergic reactions. DUPIXENT can cause allergic reactions that can sometimes be severe. Stop using DUPIXENT and tell your healthcare provider or get emergency help right away if you get any of the following signs or symptoms: breathing problems or wheezing, swelling of the face, lips, mouth, tongue, or throat, fainting, dizziness, feeling lightheaded, fast pulse, fever, hives, joint pain, general ill feeling, itching, skin rash, swollen lymph nodes, nausea or vomiting, or cramps in your stomach-area.
  • Eye problems. Tell your healthcare provider if you have any new or worsening eye problems, including eye pain or changes in vision, such as blurred vision. Your healthcare provider may send you to an ophthalmologist for an eye exam if needed.
  • Joint aches and pain. Some people who use DUPIXENT have had trouble walking or moving due to their joint symptoms, and in some cases needed to be hospitalized. Tell your healthcare provider about any new or worsening joint symptoms. Your healthcare provider may stop DUPIXENT if you develop joint symptoms.

The most common side effects in patients with eczema include injection site reactions, eye and eyelid inflammation, including redness, swelling, and itching, sometimes with blurred vision, dry eye, cold sores in your mouth or on your lips, and high count of a certain white blood cell (eosinophilia).

Tell your healthcare provider if you have any side effect that bothers you or that does not go away. These are not all the possible side effects of DUPIXENT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Use DUPIXENT exactly as prescribed by your healthcare provider. It’s an injection given under the skin (subcutaneous injection). Your healthcare provider will decide if you or your caregiver can inject DUPIXENT. Do not try to prepare and inject DUPIXENT until you or your caregiver have been trained by your healthcare provider. In children 12 years of age and older, it’s recommended DUPIXENT be administered by or under supervision of an adult. In children 6 months to less than 12 years of age, DUPIXENT should be given by a caregiver.

Please see accompanying full Prescribing Information including Patient Information.

Indication

DUPIXENT is a prescription medicine used to treat adults and children 6 months of age and older with moderate-to-severe eczema (atopic dermatitis or AD) that is not well controlled with prescription therapies used on the skin (topical), or who cannot use topical therapies. DUPIXENT can be used with or without topical corticosteroids. It is not known if DUPIXENT is safe and effective in children with atopic dermatitis under 6 months of age.

Take This Quiz to Understand Your Condition

Do you still experience symptoms of constant itching and skin flare-ups while using prescription
topical treatments? Answer a few quick questions to better understand moderate-to-severe eczema
(atopic dermatitis), and use this information to help have a discussion with a doctor.

FIND A SPECIALIST WHO
TREATS ECZEMA

Use this Healthgrades™ tool to easily find nearby specialists with
experience in treating children, teens, and adults with
uncontrolled moderate-to-severe eczema (atopic dermatitis).

Sanofi US and Regeneron do not endorse or recommend any particular physician, and search results do not include a comprehensive list of doctors in your area.

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